The effect of uterine bathing on implantation in endometriosis patients undergoing IVF/ICSI: a randomized controlled pilot trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26775

Enrollment

184

Registered

2013-10-07

Start date

2014-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subfertility, IVF/ICSI, implantation, Endometriosis.

Interventions

Patients will be randomized to undergo uterine bathing through a GIS (intervention group) or a sham procedure (control group) before treatment with IVF/ICSI. The GIS will be performed by our local pro

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 41 years old 2. Undergoing IVF/ICSI treatment 3. Endometriosis ASRM stage I-IV

Exclusion criteria

Exclusion criteria: 1. Women aged over 41 years 2. Women who are unable to undergo IVF/ICSI treatment 3. Uterus anomalies (bicornis/didelphys/septa) 4. Pregnancy or malignancy 5. Not willing or able to sign the consent form 6. Previous participation in the trial

Design outcomes

Primary

Measure	Time frame
Live birth rate after fresh embryo transfer	—

Secondary

Measure	Time frame
- Implantation rate, clinical pregnancy rate, ongoing pregnancy rate after fresh embryo transfer. - Multiple pregnancy, miscarriage and ectopic pregnancy rate after fresh embryo transfer. - Endometrial thickness at the day of Pregnyl®. - Adverse events defined as: intrauterine infection and severe bleeding after the intervention.	—

Contacts

Public ContactMarit Lier

VU Medical Centre Boelelaan 1118

ma.lier@vumc.nl020 4445278

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)