Cryo- vs surgical Lung biopsy for diagnosing interstitial lung disease: a randomized controlled trial

Bronchoscopic cryo- vs surgical Lung biopsy for diagnosing interstitial lung disease: a randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26744

Enrollment

Registered

2019-03-29

Start date

2019-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial lung disease

Interventions

Step up diagnostic strategy starting with cryobiopsy (only followed by surgical biopsy in the case of non-diagnostic cryobiopsy) vs standard (immediate surgical biopsy)

Eligibility

Inclusion criteria

Inclusion criteria: Adults with an interstitial lung disease and an indication for lung tissue sampling

Exclusion criteria

Exclusion criteria: Use of clopidogrel, or other new anti-platelet therapy, or anticoagulant drugs that cannot be stopped temporarily, thrombocytopenia ( 50 mmHg), Diffusing capacity 35, Pregnancy

Design outcomes

Primary

Measure	Time frame
Need for (prolonged) chest tube drainage	—

Secondary

Measure	Time frame
Complications, comprehensive complication index, length of hospital stay, days with chest tube, pain, quality of life, diagnostic yield, patient preference and health care costs.	—

Contacts

Public ContactMarianne van de Pol

Amsterdam UMC, locatie AMC, afdeling Longziekten

m.a.vandepol@amc.nl+31 (0)20 566 1285

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)