SDD-SOD-trial.

Selective Digestive Decontamination (SDD) and Selective Orophayngeal Decontamination (SOD) as Infection Prevention Measure in Intensive Care: Effects on Mortality and Antibiotic Resistance Development.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26718

Enrollment

3450

Registered

2005-09-06

Start date

2004-05-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients treated in Intensive Care Units.

Interventions

Selective Digestive Decontamination. Selective Oropharyngeal Decontamination.

Eligibility

Inclusion criteria

Inclusion criteria: All patients admitted to the ICU with an expected stay> 72 hours in ICU or with an expected duration of mechanical ventilation > 48 hours.

Exclusion criteria

Exclusion criteria: 1. Known allergy to study-medication in patient-history; 2. Pregnancy.

Design outcomes

Primary

Measure	Time frame
1. Hospital mortality; 2. ICU-mortality.	—

Secondary

Measure	Time frame
1. Prevalence of antibiotic resistance; 2. Duration of mechanical ventilation; 3. Duration of ICU-stay; 4. Incidence of hospital infections; 5. Antibiotic use; 6. Health care costs.	—

Contacts

Public ContactAnne Marie G.A. Smet, de

University Medical Center Utrecht (UMCU), AZU, P.O. Box 85500

a.desmet@azu.nl+31 (0)30 2509111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)