eating behaviour
Conditions
Interventions
Oral and gastric stimulation:
Subjects receive (after inclusion, IC and training session) 6 treatments. 4 treatments with 2x2 design with:
1. Oral stimulation: 1 min (low) or 8min (high) modified sh
2. Gastric stimulation: Infusion of 500ml of liquid with 100kcal or 700kcal into the stomach with a naso-gastric tube.
Besides these 4 treatments there is a control treatment: A naso-gastric tube is
Sponsors
Wageningen University, Division of Human Nutrition
Eligibility
Inclusion criteria
Inclusion criteria: 1. Gender: Male; 2. Age: ≥ 18 years and ≤ 40 years; 3. Stable body weight (change of < 5 kg body weight in the last 2 months); 4. Good physical and mental health as judged by the participant himself; 5. BMI: ≥ 18.5 and < 25 kg/m2; 6. Having signed the informed consent forms.
Exclusion criteria
Exclusion criteria: 1. Smoking or drug use; 2. Gastro-intestinal diseases; 3. Diabetes, thyroid diseases or any other endocrine disorders; 4. Lack of appetite for any reason; 5. Restraint eating DEBQ score ≥ 2.26 (above average); 6. Hypersensitivity or food allergy for products used in this study; 7. Currently participating or having participated in a clinical trial during the last 3 months prior to the beginning of this study; 8. Taking any medication, except for light pain relieving medications which are available over the counter (aspirin or paracetamol); 9. Problems with the respiratory tract, such as hyperventilation, asthma or bronchitis, which can cause problems when the naso-gastric tube is inserted; 10. Working at, or doing an MSc. thesis at the Division of Human Nutrition. Information about the exclusion criteria above is requested from the subjects via an inclusion/screening questionnaire. This information is checked at the first visit of the subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ad libitum energy intake of an ad libitum test meal served 30 minutes after start of the treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the effect of short/long oro-sensory exposure combined with a gastric load low/high in energy, on: 1. Subjective feelings of satiety; 2. Gastric emptying rate; 3. Furthermore we want to reproduce the results of one treatment (1min/800ml) of our previous study, to investigate the gastric emptying rate in this condition. | — |
Contacts
Public ContactAnne Wijlens
PO Box 8129
Outcome results
None listed