Scars, scar formation, burns, burn scars, adherent scar
Conditions
Interventions
Patients will receive SVF enriched fat graft injection (ratio SVF: fat =1:10) underneath an adherent scar.
Sponsors
ZonMw, Nederlandse Brandwondenstichting
Eligibility
Inclusion criteria
Inclusion criteria: • Patients seen by a plastic surgeon in Burn Centre Beverwijk or Groningen • Patient is = 18 years old • Patient has an adherent scar (minimum scar age: 12 months) caused by burns, necrotic fasciitis or degloving injury, for which fat grafting is indicated • Competent adults
Exclusion criteria
Exclusion criteria: • Previous scar treatment with fat grafting in selected scar • General exclusion criteria for fat grafting procedure: pregnancy, BMI < 18 • Skin melanoma in patient’s history • Unwillingness to commit to the study protocol and show up for all follow up moments • Insufficient proficiency in Dutch to the extent that clear communication is not possible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pliability by the cutometer | — |
Secondary
| Measure | Time frame |
|---|---|
| POSAS questionnaires, both observer as patient questionnaire. DSM colormeter Cutometer other variables Immunohistological stainings of biopsies. RNA isolation out of biopsies. | — |
Contacts
Public ContactLinda Vriend
University and Medical Center Groningen
Outcome results
None listed