English keywords: - MRDTI - cerebral vein thrombosis - diagnostic Dutch keywords: - MRDTI - cerebrale veneuze trombose - diagnostiek
Conditions
Interventions
This study is a prospective, multicenter diagnostic proof of concept study to explore the diagnostic accuracy of MRDTI/BTI in the diagnostic management of suspected CVT and an indication for MRV, whic
Sponsors
Leiden University Medical Center (LUMC)
Eligibility
Inclusion criteria
Inclusion criteria: - Patients with clinically suspected first or recurrent CVT who are referred for MRV scan because of: o Inconclusive CTV scan, as judged by the (neuro-)radiologist, OR o Patients with a contraindication for CTV (i.e. contrast allergy, pregnancy) - Aged 18 years and older - Willing and able to give informed consent
Exclusion criteria
Exclusion criteria: - A medical condition, associated illness or co-morbid circumstances that precludes completion of the study procedures (MRI and 90-day follow-up assessment), including but not limited to life-expectancy less than 3 months, inability to lie flat, morbid obesity preventing use of MR and claustrophobia; - Non-diagnostic MRV as judged by the (neuro-)radiologist.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The sensitivity and specificity of MRDTI for the diagnosis of CVT in patients with suspected first or recurrent CVT and an indication for MRV | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Achievement of a reproducible MRDTI/BTI scan sequence for CVT; 2) To assess the interobserver agreement of the readers of MRDTI/BTI for suspected CVT. | — |
Contacts
Public ContactLisette van Dam
Outcome results
None listed