Colorectal cancer, screening, FIT
Conditions
Interventions
For this study, 10.000 individuals will be invited for CRC screening by FIT (OC-sensor).
Sponsors
Initiator: Academic Medical Centre (AMC), departement of Gastroenterology & Hepatology. Co-centre: Flevoziekenhuis Almere
Eligibility
Inclusion criteria
Inclusion criteria: 1. Asymptomatic individuals between 50 and 74 years of age; 2. Individuals living in the target area (similar to 1st and 2nd round): Amsterdam, Almere, Watergraafsmeer and Diemen; 3. Non-responders to the 1st and/or 2nd round; 4. Responders to 1st and/or 2nd round; 5. First-time invitees (persons aged 50–75 that moved into the target area or persons that turned 50 within the last 2 years).
Exclusion criteria
Exclusion criteria: 1. FIT positive in 1st or 2nd round; 2. Complete colonoscopy or CT colonography performed within the last 2 years; 3. Personal history of colorectal cancer; 4. Severe co-morbidity (ASA IV/V); 5. Terminal disease (life-expectancy < 5 years); 6. Inability or refusal to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Participation rate. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Evaluation of the diagnostic yield of FIT; 2. Evaluation of the reasons for non-participation; 3. Evaluation of the interval carcinomas during three subsequent screening rounds. | — |
Contacts
Public ContactE. Dekker
PO Box 22700
Outcome results
None listed