Kan warmte post-prandiale endotheel dysfunctie voorkomen?

Can heating prevent hyperglycaemia-induced endothelial dysfunction?

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON26610

Enrollment

Registered

2014-06-06

Start date

2014-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-prandiale endotheel dysfunctie

Interventions

Local heating

Eligibility

Inclusion criteria

Inclusion criteria: Diabetes group: - Older than 40 years - Diagnosed with type 2 diabetes mellitus at least 2 years ago Control group: - Older than 40 years (ensure matching with diabetes group at group level)

Exclusion criteria

Exclusion criteria: Diabetes group: - Women - Cardiovascular disease - Hypercholesterolemia - Hypertension (>160 mmHg systolic and/or >90 mmHg diastolic pressure) and/or subjects on antihypertensive drugs - Smoking - Type I diabetes mellitus - Older than 70 years - Subjects with vascular complications due to type 2 diabetes mellitus (e.g. diabetic foot ulcer) - Subjects using insulin injections to regulate glucose homeostasis Control group: - Women - Cardiovascular disease - Hypercholesterolemia - Hypertension (>160 mmHg systolic and/or >90 mmHg diastolic pressure) and/or subjects on antihypertensive drugs - Smoking - Older than 70 years

Design outcomes

Primary

Measure	Time frame
Change in endothelial function (measured as flow-mediatd dilation) after a meal (induced by 75-gr glucose ingestion)	—

Secondary

Measure	Time frame
Blood flow and skin temperature changs	—

Contacts

Public ContactDick H.J. Thijssen

Phililps van Leijdenlaan 15

d.thijssen@fysiol.umcn.nl+31 (0)24 3614222

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)