Patients undergoing abdominal surgery
Conditions
Interventions
Hemodynamic guidance based on arterial blood pressure or cardiac output with pulse pressure variation.
1. Mean Arterial Pressure (MAP), measured with a non-invasive continuous arterial sphygmomanomet
2. Pulse Pressure Variance (PPV), also measured with a non-invasive continuous arterial sphygmomanometer.
Sponsors
VU University Medical Center
Westfries Gasthuis Hoorn
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective abdominal surgery; 2. Age 18-85 years; 3. Duration of surgery > 90 minutes; 4. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Preexisting cardiac arrhythmias; 2. Emergency operation; 3. ICU patients; 4. Body mass index below 20 kg/m2 and above 40 kg/m2; 5. Patients without an invasive arterial line; 6. Decompensatio cordis; 7. Aortic valve disease; 8. Ejection fraction 30 mm Hg, TAPSE < 18 mm; 11. Incapacitated patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is defined as postoperative morbidity based on the incidence of a number of predefined complications until 7 days after surgery. These parameters include, among others, reoperation, infections, rehabilitation and restoration of gastrointestinal function. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include hospital length of stay and microcirculatory perfusion. | — |
Contacts
Public ContactChrista Boer
VU University Medical Center, Department of Anesthesiology
Outcome results
None listed