Early or Late Intervention in high risk non ST elevation Acute Coronary Syndromes.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26567

Enrollment

540

Registered

2006-07-31

Start date

2006-08-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high risk non-ST elevation acute coronary syndrome patients

Interventions

Immediate angiography and revascularization reduces compared to delayed angiography not earlier than 48 hours after admission.

Eligibility

Inclusion criteria

Inclusion criteria: Ischemic Chest Pain or Dyspnoe at rest with last attack 5 mm or ii. Temporary ST segment elevation in 2 contiguous leads 0.05 ng/ml) or Myoglobin (>150 microg/l) on admission or 3 hours later or ii. Positive CKmb fraction on admission (>6% of total CK); 3. Age above 65 years.

Exclusion criteria

Exclusion criteria: 1. Persistent ST segment elevation; 2. Absolute contra-indication for diagnostic angiography.; 3. Active bleeding; 4. Cardiogenic shock; 5. Acute posterior infarction; 6. Live expectancy less than 1 year.

Design outcomes

Primary

Measure	Time frame
Combined incidence of death, re-infarction and hospitalization for recurrent ischemia at 30 days follow-up.	—

Secondary

Measure	Time frame
1. Enzymatic Infarct Size as assessed by a single cardiac Troponin T, measured at 72-96 hours after admission or at discharge; 2. The percentage of patients without a rise in CKmb during admission.	—

Contacts

Public ContactJ. Brinkhuis

Diagram B.V., v. Nahuysplein 6

j.brinkhuis@diagram-zwolle.nl+31 (0)38 4262994

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)