addiction relapse stress recreational drug users healthy controls
Conditions
Interventions
1.placebo
2. methylphenidate
3. hydrocortisone
4. methylphenidate + hydrocortisone
Sponsors
Forschungszentrum Juelich
Eligibility
Inclusion criteria
Inclusion criteria: -bloodscreen (normal level) -thyroidal parameters (normal level) -ECG (normal level) -negative drugscreen in urine (Benzodiazepine, Opiate, Amphetamine, Cannabis). -no nephrological or thyroidal diseases in medical history -no metal in the human body -no tattoos -age between 18 and 40 years -Body Mass Index (BMI) between 18 und 28 -no first degree relatives with psychiatric disorders in medical history -no psychiatric or neurological disorders in medical history -righthandedness -native German speakers For women: negative pregnancy test For recreational drug users: experience with psychostimulants
Exclusion criteria
Exclusion criteria: -volunteers who are unable to sign the informed consent -pregnancy -volunteers under the age of 18 years -magnetic metal implants, contraceptive coil, tattoos -colorblindness For recreational drug users: drug addiction or dependence in medical history
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -imaging results under the influence of a psychostimulant, a stress hormone or both. | — |
Secondary
| Measure | Time frame |
|---|---|
| -behavioural performance on cognitive tasks under the influence of a psychostimulant, a stress hormone or both. | — |
Contacts
Public ContactWendy Bosker
Outcome results
None listed