Esophageal Adenocarcinoma (EAC), Esophagectomy, Slokdarmkanker, Endoscopic Ultrasound
Conditions
Interventions
To study the resectability of an esophageal adenocarcinoma, patients will undergo an endoscopic re-assessment by high resolution endoscopy. This is a standard procedure
no new interventions will be used.
Sponsors
Erasmus Medical Center Rotterdam
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged > 18 years, with a biopsy proven esophageal adenocarcinoma, staged as a cT2N0M0 lesion.
Exclusion criteria
Exclusion criteria: - Presence of metastasize disease - Presence of (cytology proven) lymph node metastasis - Presence of a stenosis, inhibiting the passage of a gastroscope - Presence of esophageal varices (inhibiting endoscopic resection) - Known or suspected esophageal perforation - Anti-coagulant therapy (apart from aspirin or NSAID) that cannot be discontinued prior to ER, or uncorrectable hemostatic disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To prospectively evaluate the value of an endoscopic reassessment of patients with an initial diagnosis of a cT2 EAC by an experienced therapeutic endoscopist, followed by ER of the lesion if deemed possible. Expressed as the number of lesions that are downstaged to a T1 lesion after reassessment and endoscopic resection. | — |
Secondary
| Measure | Time frame |
|---|---|
| To prospectively evaluate the number of lesions that are within currently accepted criteria for endoscopic resection | — |
Contacts
Public ContactSteffi van de Ven
Gastroenterology and Hepatology department P.O. Box 2040
Outcome results
None listed