Non-invasive measurement of mitochondrial oxygenation in patients with Complex Regional Pain Syndrome

COMET in CRPS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON26528

Enrollment

Registered

2020-01-30

Start date

2020-01-16

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complex Regional Pain Syndrome

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients with CRPS • Diagnosed with CRPS according to the new IASP criteria. We will only include patients that still meet these criteria. • Clinically the contralateral extremity must be without signs or symptoms in a way that it can be used as a control • Signed informed consent Healthy controls • Signed informed consent

Exclusion criteria

Exclusion criteria: Patients with CRPS • < 18 years of age • Presence of mitochondrial disease • Porphyria Healthy controls • < 18 years of age • Presence of mitochondrial disease • Porphyria • (Consideration of) diagnosis of CRPS in history

Design outcomes

Primary

Measure	Time frame
MitoPO2 and mitoVO2	—

Secondary

Measure	Time frame
• Demographic parameters such as: age, sex, smoking and consumption of alcohol • General medical history and medication use • CRPS severity score • Videothermography image of the affected and contralateral extremity	—

Contacts

Public ContactElse Bijl

Erasmus MC

e.bijl@erasmusmc.nl+31650032166

Outcome results