Vitamin D, UVB irradiation, dementia, well-being, nursing home, long-term care
Conditions
Interventions
The intervention consists of half-body UVB irradiation, two times a week, over 6 months, with 0.5 minimal erythemal dose (MED), compared to oral supplementation with 5600 IE cholecalciferol once a wee
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: • > 70 years of age
Exclusion criteria
Exclusion criteria: • contraindications against ultraviolet radiation: actinic damaged skin including, skin cancer, sun allergy, porphyrias, use of drugs that can induce photodermatoses. • contraindications to treatment with vitamin D3 such as hypercalcemia and sarcoidosis • the use of vitamin D fortified supplementary feeding • in the context of the underlying dementia, frequent anxiety or fear or aggression and known resistance to physical contact (e.g. blood tests)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Well-being, monitored with the CMAI (Cohen-Mansfield Agitation Inventory) and the Cornell scale for depression in dementia at 0, 3 and 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Vitamin D status • Calcium homeostasis | — |
Contacts
Public ContactB. Veleva
Leiden University Medical Center Dept. Public Health and Primary Care
Outcome results
None listed