Timing of PEG tube placement in patients with amyotrophic lateral sclerosis: soon or later?

Earlier PEG placement in ALS patients with dysphagia: effects on survival, nutritional and functional status, and quality of life

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26494

Enrollment

Registered

2007-01-15

Start date

2004-08-04

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with Amyotrophic Lateral Sclerosis (ALS) and dysphagia

Interventions

Early PEG (PEG placement within 4 weeks after inclusion) versus a "wait and see approach", with probably a PEG placement at a later stage

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with possible, probable, probable lab supported, or definite ALS; 2. Dysphagia Hillel score 7 or 8 (ALSSS dyspagia subscale); 3. Vital capacity >65%; 4. Age > 18 yr and < 85 yr; 5. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Contra-indication for PEG

Design outcomes

Primary

Measure	Time frame
Survival	—

Secondary

Measure	Time frame
1. Vital capacity; 2. BMI; 3. Triceps skinfold; 4. ALSFRS; 5. VAS Q0L; 6. SF 36;	—

Contacts

Public ContactM.M. Graaff, van der

Academic Medical Centred, department of Neurology PO box 22660

m.m.vandergraaff@amc.uva.nl+31205663647

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)