Study of the immune system following spinal cord injury

Characterisation of the immune response after spinal cord injury

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON26426

Enrollment

102

Registered

2020-06-03

Start date

2020-09-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: - Individuals older than 18 years - Diagnosis of spinal cord injury.

Exclusion criteria

Exclusion criteria: - Individuals with pre-existing autoimmune diseases - Use of anti-inflammatory or immune modulatory treatment.

Design outcomes

Primary

Measure	Time frame
- Identification of the autoantibodies produced after SCI. - Characterisation of the autoantibody response after SCI in patients over time. - Assessment of the association between clinical outcome parameters and changes in antibody levels: determining the prognostic biomarker potential of the candidate biomarkers.	—

Secondary

Measure	Time frame
- Determine immune cell subtypes and function, immune derivatives, inflammatory and neurological markers in peripheral blood at multiple time points following spinal cord injury. - Assessment of the association between the clinical outcome parameters and the changes in immunological and neurological parameters in SCI patients.	—

Contacts

Public ContactVeerle Somers

Hasselt University

veerle.somers@uhasselt.be003211269202

Outcome results