Transitional Pain Service for patients at Risk of chronic postsurgical pain Undergoing Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26410

Enrollment

180

Registered

2020-08-28

Start date

2020-12-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic postoperative pain

Interventions

Patients will be randomized to the TPS group or standard of care group. Patients allocated to the standard of care group will receive a pre-assessment at the outpatient preoperative evaluation (OPE) c

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 years or older 2. Willing and able to provide informed consent 3. Undergoing a surgical procedure with an increased risk of CPSP (amputation, spinal surgery, thoracotomy, breast surgery, herniotomy, hysterectomy and after arthroplasty) (9). Or; Any surgical procedure and one of the following: - Diagnosed chronic pain, defined according to the ICD-11 as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Chronic pain is pain that persists or recurs for longer than 3 months (3)” - Chronic opioid use, defined as > 20 mg daily morphine equivalent (MME) consumption for more than 3 months in the last 3 months - Allergy to opioid agents - Patients with pain device implants, such as intrathecal pain pump, spinal cord stimulation or peripheral nerve stimulator - The usage of pain medication as methadone, buprenorphine, anticonvulsants, antidepressants or medicinal cannabis for chronic pain for more than 3 months in the last three months Psychosocial comorbidities like anxiety, depression, pain catastrophizing if documented in the electronic medical record

Exclusion criteria

Exclusion criteria: - Not willing or able to provide written informed consent - Emergency surgery

Design outcomes

Primary

Measure	Time frame
The primary outcome is the between group difference in Quality of Recovery (QoR)-15 questionnaire score at day three after surgery.	—

Secondary

Measure	Time frame
- Postsurgical chronic pain (CPSP) at three and six months after surgery, defined according to the IASP (as mentioned in chapter 1), and/or taking pain medication to treat CPSP as described above. - Opioid consumption per day, calculated as morphine equivalent dose (MEDs) at day three after surgery, prescription at discharge, and at three and six months after discharge. - Patient-reported outcome as measured by the WHODAS 2.0 (15), PROMIS-29 (16) and EQ-5D-5L (17) preoperatively and at three and six months after discharge.	—

Measure

Time frame

- Postsurgical chronic pain (CPSP) at three and six months after surgery, defined according to the IASP (as mentioned in chapter 1), and/or taking pain medication to treat CPSP as described above. - Opioid consumption per day, calculated as morphine equivalent dose (MEDs) at day three after surgery, prescription at discharge, and at three and six months after discharge. - Patient-reported outcome as measured by the WHODAS 2.0 (15), PROMIS-29 (16) and EQ-5D-5L (17) preoperatively and at three and six months after discharge.

—

Contacts

Public ContactManouk Admiraal

Amsterdam UMC, locatie Meibergdreef

m.admiraal1@amsterdamumc.nl0682346824

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)