chronic ITP platelet function Immune thrombocytopenia fatigue
Conditions
Interventions
An extra blood sample withdrawal during a routine venipuncture (as part of standard of care), the ITP-bleeding assessment tool (ITP-BAT) and two questionnaires. Women will be asked to fill out an extr
Sponsors
University Medical Center Utrecht
Eligibility
Inclusion criteria
Inclusion criteria: -Age 16 years and older -Previously confirmed diagnosis of chronic primary ITP with current platelet counts of <100x109/L or currently on (any) treatment for chronic ITP -Willing and able to understand the study information and sign the informed consent form.
Exclusion criteria
Exclusion criteria: There are no additional exclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess platelet function and coagulation parameters in adult chronic ITP patients in relation to their bleeding phenotype | — |
Secondary
| Measure | Time frame |
|---|---|
| -To assess immune profiles in chronic ITP patients and explore for imbalances between effector cells and regulatory cells -To validate the CIS-20 fatigue subscale in chronic ITP patients by comparing it to the FACIT-F -To assess the prevalence of menorrhagia in female chronic IT patients and the impact on daily life -To compare fatigue in chronic ITP patients with fatigue in healthy controls and other chronically ill patients | — |
Contacts
Public ContactWobke Dijk, van
Divisie Interne Geneeskunde en Dermatologie, Van Creveldkliniek, Universitair Medisch Centrum Utrecht, Huispostnummer C.01.428
Outcome results
None listed