Stimuleren van het onwillekeurige zenuwstelsel bij patienten die een darmoperatie ondergaan.

Stimulation of the autonomic nervous system in colorectal surgery.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON26402

Enrollment

120

Registered

2011-04-26

Start date

2008-10-03

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative ileus, postoperatieve ileus inflammation, ontsteking colorectal surgery, colorectale chirurgie intestinal damage, darmschade enteral nutrition, enterale voeding

Interventions

Intervention group: Patiënts will receive chewing gum pre-operative from the moment they are sober untill the operation. They will start again four hours after the operation untill normal food is agai

Eligibility

Inclusion criteria

Inclusion criteria: 1. Resectable colorectal carcinoma; 2. Age >18 years.

Exclusion criteria

Exclusion criteria: 1. Previous esofageal/ stomach surgery; 2. Neurological disorders influencing acetylcholine metabolism; 3. Use of SSRI; 4. Depression; 5. Inflammatory bowel disease; 6. Medication influencing gut motility; 7. Allergy for mint; 8. Metastatic disease; 9. Stoma.

Design outcomes

Primary

Measure	Time frame
1. Lenght of stay; 2. Time to first flatus/ defaecation; 3. Infectious complications.	—

Secondary

Measure	Time frame
1. Effect on inflammation (cytokines); 2. Effect on intestinal damage; 3. Effect on gastrointestinal passage (ultrasound); 4. Morbidity and mortality.	—

Contacts

Public ContactMisha Luyer

Catharina ziekenhuis Eindhoven Michelangelolaan 2

m.luyer@maastrichtuniversity.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)