Rheumatoid Arthritis, Cardiovascular disease, Exercise therapy, Inflammation, Cardiorespiratory fitness, Reumatoïde Artritis, Cardiovasculaire ziekte, Oefentherapie, Ontsteking, Cardiorespiratoire fitheid
Conditions
Interventions
The exercise therapy program will include exercises that are primarily aimed at improving cardiorespiratory fitness and functional performance in RA patients. Frequency, intensity, time, type and prog
Sponsors
Reade Center of Rehabilitation and Rheumatology
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of RA fulfilling the ACR/EULAR classification criteria, high 10-year CV risk (≥20%) calculated with the Dutch SCORE table, age >20 and <80 years
Exclusion criteria
Exclusion criteria: Comorbidity which severely affects functional ability (CIRS≥2), K&L grading of ≥3 for hip and/or knee OA, contra-indication for exercises according to the ACSM guideline (Durnstine 2009) i.e., progressive increase in heart failure symptoms, myocardial infarction less than 3 months before the start of the training program, severe ischemia of the cardiac muscle upon exertion, respiratory frequency of more than 30 breaths per minute and heart rate at rest >110 bpm, insufficient control of the Dutch language and/or cognitive problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of the study is cardiorespiratory fitness assessed with a graded exercise tolerance test on an exercise bike (Lode, the Netherlands). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are functional performance, CV risk factors and disease activity. | — |
Contacts
Public ContactLisa Edelaar
Outcome results
None listed