Colorectal cancer, low anaerobic threshold Colorectaal kanker, lage anaerobe drempel
Conditions
Interventions
The primary endpoint of this study is the number of postoperative complications within 30 days after elective colorectal surgery.
In this study, 42 patients will receive 4 weeks of physiotherapy befo
Sponsors
Medisch Spectrum Twente, surgery department.
Eligibility
Inclusion criteria
Inclusion criteria: -Older than 18 years; -Colon or rectal cancer; -Undergoing elective colorectal surgery; -Having a life expectancy of more then 6 months; -Has given consent to participate in the study; -Metabolic equivalent score </=7 on the Veterans Specific Activity Questionnaire; -Anaerobic threshold < 11 ml/kg/min after the first CPET; -Able to perform a cardiopulmonary exercise test; -Will be operated at Medisch Spectrum Twente at Enschede.
Exclusion criteria
Exclusion criteria: -Anaerobic threshold >= 11 ml/kg/min after the first CPET; -Not capable to perform a cardiopulmonary exercise test; -Undergoing emergency colorectal surgery; -Meeting the absolute and/or relative exclusion criteria from the CPET protocol used in Medisch Spectrum Twente. These criteria are based on the criteria from the American Thoracic Society and American College of Chest Physicians Statement on CPET.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative complications (pulmonary, renal, gastrointestinal, infective, cardiovascular, neurological, haematology, pain, wound) within 30 days after surgery in group A and B. | — |
Secondary
| Measure | Time frame |
|---|---|
| -Improvement of AT after the prehabilitation program in the intervention group; -Natural decline of the cardiopulmonary fitness in the control group by measuring the anaerobic threshold after diagnosis of colorectal cancer and 4 weeks later; -Length of stay in hospital after surgery; -Postoperative complications within 30 days after surgery in patients with an anaerobic threshold ¡Ý 11 ml/kg/min after the first CPET; -Improvement of the inspiratory muscle strength after cardio-fitness training. | — |
Contacts
Public ContactJ.M. Klaase
Medisch Spectrum Twente Oncology surgeant Postbus 50 000
Outcome results
None listed