Response evaluation after chemoradiation for advanced oropharyngeal cancer using PET-CT and MRI

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON26306

Enrollment

Registered

2014-07-28

Start date

2012-05-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Squamous cell carcinoma (SCC), oropharynx

Interventions

PET-CT, MRI and examination under general anesthesia three months after treatment

Eligibility

Inclusion criteria

Inclusion criteria: • Oropharyngeal squamous cell carcinoma • Initially resectable • Scheduled for chemoradiation • ‘Informed consent’ signed by patient

Exclusion criteria

Exclusion criteria: • Age < 18 years • Pregnancy • Physical condition contra-indication salvage surgery • Contra-indication for MRI

Design outcomes

Primary

Measure	Time frame
The primary endpoint is: accuracy with which diagnostic tests reduce the number of avoided futile EUAs.	—

Secondary

Measure	Time frame
Secondary endpoints are: interobserver agreement, SUV (FDG-PET) and ADC (DW-MRI) thresholds, associated costs and burden of diagnostic procedures and health related quality of life.	—

Contacts

Public ContactC.S. Schouten

Department of Otolaryngology/ Head and Neck surgery VU University Medical Center

cs.schouten@vumc.nl+31204440954

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)