Endometrial cancer, endometrial hyperplasia and endometrial intraepithelial Neoplasia (EIN)
Conditions
Interventions
Women with a planned, standard samplig procedure are recruited. No additional interventions are done for the purpose of the study.
Sponsors
Erasmus MC
Eligibility
Inclusion criteria
Inclusion criteria: Patients, aged 40 years and older, visiting the outpatient clinic with any indication for endometrial biopsy following the Dutch guidelines and common practice. At the distinction of the gynaecologist samples are either obtained by an office sampling device, or by hysteroscopy.
Exclusion criteria
Exclusion criteria: Age < 40 Not able to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -What is the accuracy of the EIN diagnosed in an office setting (sampling devices and hysteroscopic biopsies)? | — |
Secondary
| Measure | Time frame |
|---|---|
| - What is the risk of a malignancy after EIN in samples obtained in an office setting (office endometrial sampling as well as hysteroscopy)? - Do samples obtained in an office setting (office endometrial sampling as well as hysteroscopy) contains sufficient material to diagnose EIN? - How do EIN and hyperplasia correlate in samples obtained in an office setting (office endometrial sampling as well as hysteroscopy)? - Do gynaecologist adhere to the current Dutch guideline postmenopausal bleeding (11.2015) | — |
Contacts
Public ContactLena van Doorn
ErasmusMC Cancer Institute
Outcome results
None listed