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The effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomised controlled trial.

The effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomised controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON26297
Enrollment
100
Registered
2005-09-12
Start date
2002-06-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subfertility

Interventions

Couples were randomly allocated to IUI for six months or expectant management for six months. In the first three IUI cycles no controlled ovarian hyperstimulation (COH) was given. If these attempts fa

Sponsors

OFO-project t.a.v. B.W. Mol Academic Medical Center Center of Reporductive medicine, H4-213 Postbus 22660 1100 DD Amsterdam Phone: 0031205663857 Fax: 0031206963489 e-mail: ofoproject@amc.uva.nl or b.mol1@chello.nl
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Couples with a cervical factor and otherwise no factors that reduced their fertility, i.e. a prognosis for a treatment independent ongoing pregnancy in the next year higher than 30%. A cervical factor was diagnosed by a well-timed, non-progressive post-coital test (PCT) with normal semen parameters.

Exclusion criteria

Exclusion criteria: All other subfertile couples.

Design outcomes

Primary

MeasureTime frame
The primary endpoint was ongoing pregnancy within six months. Ongoing pregnancy was defined as the presence of foetal cardiac activity at transvaginal sonography at a gestational age of at least 12 weeks.

Secondary

MeasureTime frame
Secondary endpoints were total number of clinical pregnancies, miscarriages and multiple pregnancies.

Contacts

Public ContactP. Steures

Academic Medical Center (AMC), Center of Reproductive medicine, OFO-project, H4-213, P.O. Box 22660

pn.steures@amc.uva.nl / ofoproject@amc.uva.nl+31 (0)20 5663857

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)