Vasa studie.

Vascular contrast-enhanced ultrasound.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON26282

Enrollment

200

Registered

2010-03-01

Start date

2010-03-15

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient from the outpatient clinic of Cardiology and Vascular Medicine with hypertension, diabetes mellitus, hypercholesterolemia, smoking, and/or a family history of cardiovascular disease

Interventions

This is an observational study, no interventions are planned.

Eligibility

Inclusion criteria

Inclusion criteria: 1. >18 years of age; 2. Presence of cardiac risk factors.

Exclusion criteria

Exclusion criteria: 1. Unstable clinical symptoms; 2. Contraindications for contrast-enhanced ultrasound.

Design outcomes

Primary

Measure	Time frame
1. A quantification method for vasa vasorum imaging using contrast-enhanced ultrasound of the carotid arteries will be developed, using physical ultrasound parameters; 2. The vessel wall thickness (intima-media thickness) and vasa vasorum will be evaluated in patients with hypertension, diabetes mellitus, hypercholesterolemia, smoking, and/or a family history of cardiovascular disease to assess the incidence and prevalence of an increased density of the vasa vasorum network; 3. A follow-up study will be performed to evaluate a relation between ultrasound parameters and prognosis.	—

Measure

Time frame

1. A quantification method for vasa vasorum imaging using contrast-enhanced ultrasound of the carotid arteries will be developed, using physical ultrasound parameters; 2. The vessel wall thickness (intima-media thickness) and vasa vasorum will be evaluated in patients with hypertension, diabetes mellitus, hypercholesterolemia, smoking, and/or a family history of cardiovascular disease to assess the incidence and prevalence of an increased density of the vasa vasorum network; 3. A follow-up study will be performed to evaluate a relation between ultrasound parameters and prognosis.

—

Secondary

Measure	Time frame
1. Side-effects will be registered; 2. Image quality and interpretability will be evaluated. Other study parameters: 1. Demographics, gender, age, body-mass index; 2. Cardiovascular risk profile (SCORE).	—

Contacts

Public ContactArend F.L. Schinkel

's-Gravendijkwal 230 Thoraxcenter Room Ba304

a.schinkel@erasmusmc.nl+31 (0)10 7033986

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)