All patients with a suspicious or known (pre)malignant esophageal squamous cell lesion
Conditions
Interventions
Endoscopic photos and videos of white light endoscopy (WLE), magnification endoscopy, NBI and lugol’s iodine staining from previously treated patients with ESCC will be collected. The photos and video
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Western patients with a suspicious or known (pre)malignant esophageal squamous cell lesion - Photos and videos available using WLE, magnification endoscopy, NBI, and (when available) lugol’s iodine staining.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from any analysis with regard to the prediction of invasion depth: - No data on histological invasion depth available. - Patients who underwent esophagectomy with neoadjuvant (chemo)radiation therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The overall accuracy of the JES-classification for predicting the invasion depth of ESCC | — |
Secondary
| Measure | Time frame |
|---|---|
| - Presence and size of avascular areas in the esophageal squamous cell lesions. - Paris-classification of the esophageal squamous cell lesions. - Presence of intervascular background coloration. - Positive/negative pink color sign with Lugol’s iodine staining. - The predicted invasion depth of the esophageal squamous cell lesions considering the above mentioned parameters. - Inter- and intraobserver agreement between Western expert endoscopists and non-expert endoscopists, and Japanese endoscopists. | — |
Contacts
Public ContactIlse Beaufort
St. Antonius Ziekenhuis
Outcome results
None listed