Heathy term infants with intercurrent diseases: diarrhoea and respiratory infections.
Conditions
Interventions
Supplementation of infant formula with an combination of pre- and probiotics.
Sponsors
Sponsor: Dr R te Biesebeke
Global Development Centre
P.Stuyvesantweg 1
Leeuwarden
8937 AC
Netherlands
rob.tebiesebeke@frieslandfoods.com
Performer: Dr Diny van Zoeren-Grobben
Isala Clinics
Neonatal Unit
Dr van Heesweg 2
Zwolle
8025 AB
Netherlands
Tel: *31-38-4247073
Fax: *31-38-4247667
Email: d.van.zoeren@isala.nl
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy term infants with a postmenstrual age of 37-42 weeks 2. Birth weight between P10 and P90 3. Informed consent of both parents
Exclusion criteria
Exclusion criteria: 1. Neonatal sepsis 2. Severe congenital malformations 3. Birth asphyxia (apgar < 6 at 5 minutes, and/or umbilical cord pH < 7.00 and/or necessity of reanimation) 4. Admission to a pediatric ward 5. No Dutch or English speaking parents 6. Antibiotics to the mother during labour 7. Antibiotics to the infant in the first week of life 8. History of allergy with parents or sibs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Frequency, incidence and duration of diarrhoea and respiratory infections composition of gut flora | — |
Secondary
| Measure | Time frame |
|---|---|
| - Growth (head circumference, lenght and weight) - Feeding tolerance (pattern of defecation, consistence of faeces, crying, vomiting, stomach ache) | — |
Contacts
Public ContactR. Biesebeke, te
Friesland Foods Pieter Stuyvesantweg 1
Outcome results
None listed