(Remitted) Major Depressive Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years 2. Recurrent MDD diagnoses (according to DSM-IV and SCID) 3. At least 3 previous MDD-episodes (assessed with the SCID-interview) 4. In stable remission: does not meet criteria for a current MDD episode (SCID-interview) =8 weeks and a Hamilton Depression Rating Scale score =10 5. In possession of smartphone and experienced in use thereof
Exclusion criteria
Exclusion criteria: 1. Diagnosis of bipolar, primary psychotic or borderline personality disorder or strong suspicion of this type of disorder 2. Primary diagnosis of substance use or anxiety disorder with secondary MDD 3. Electroconvulsive therapy within two months before inclusion 4. Average alcohol intake of >3 units/day 5. Daily use of benzodiazepines (=5mg diazepam or equivalent) 6. Incompatible smartphone to install BEHAPP
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Focus-groups BEHAPP acceptability – saturation of ideas obtained in the focus-groups 2.BEHAPP and prediction of prospective recurrence during an observational follow-up of 1.5 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. BEHAPP and prediction of recurrence during follow-up related to residual symptoms (HDRS17) and changes in baseline ESM-based symptom-networks (daily positive and negative affect measurement) across a six-day period | — |
Contacts
Radboudumc & Donders Institute for Brain, Cognition and Behavior, Radboud University