High risk patients undergoing elective cardiac surgery.
Conditions
Interventions
All patients receive an oral nutritional supplement for at least 5 days with a maximum of 10 days before their operation in addition to their normal diet. One treatment group received a supplement tha
Sponsors
Academic Medical Centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged >= 70 years undergoing coronary bypass grafting, or pre-operative fraction < 0.40 or patients undergoing mitral valve replacements or combinations.
Exclusion criteria
Exclusion criteria: 1. Age <21 years; 2. Pregnancy; 3. Insulin depedent diabetes mellitus; 4. Hepatic cirrhosis; 5. Known malignancy; 6. Use of chemotherapy, NSAIDs or corticosteroids; 7. Schizophrenia; 8. Severe renal failure; 9. Patients with organ transplantation in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative morbidity, e.g. infectious morbidity & organ (dys)function. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Immunological parameters (inflammatory response); 2. ICU and hospital stay of length. | — |
Contacts
Public ContactRobert Tepaske
Academic Medical Center (AMC), Department of Intensive Care, C3-324, P.O. Box 22660
Outcome results
None listed