Primary brain tumor
Conditions
Interventions
None listed
Sponsors
St Elisabeth Hospital, Tilburg
Tilburg University
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients with supratentorial gliomas and meningiomas undergoing resective surgery in the St. Elisabeth Hospital, Tilburg. Eligible subjects for the control group (recruited from the general population and matched for age, gender and educational level) should be in good health, with no current or past psychiatric, neurologic, or cognitive disorder, and medication-use that interferes with cognitive function.
Exclusion criteria
Exclusion criteria: Patients and Dutch control subjects will be excluded if 1) they lack of basic proficiency in Dutch, 2) they have an IQ below 85 or low cognitive skills, 3) their Karnovsky Performance Scale is under 60, 4) they are completely unfamiliair with the use of computers, 5) they have an additional (history of) significant neurological or psychiatric disorder, 6) there is a surgery related complication (morbidity or mortality).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in objective cognitive functioning from pre-surgery to post-surgery, as measured with a computerized neuropsychological test battery, CNS Vital Signs. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression, anxiety, subjective cognitive complaints, fatigue, community integration and professional functioning, as measured with the Hospital Anxiety and Depression Scale (HADS), the Cognitive Failures Questionnaire (CFQ), Multidimensional Fatigue Inventory (MFI), Community Integration Questionnaire (CIQ), Work Ability Index (WAI) and Work Limitations Questionnaire (WLQ) respectively. | — |
Contacts
Public ContactKarin Gehring
Tilburg University - department of Cognitive Neuropsychology - Simon building - room S 219
Outcome results
None listed