Older adults, postoperative cognitive decline, functional decline, inflammatory response, onco-geriatric patients, surgery
Conditions
Interventions
None listed
Sponsors
University of Groningen
Eligibility
Inclusion criteria
Inclusion criteria: • surgery is scheduled more than 24 hours after inclusion in the study as we feel this is the time necessary to obtain test results and plan the intraoperative recording of data. • surgery under general, local or regional anaesthesia. • written informed consent given according to local regulations. • Patients can only be included in this trial once.
Exclusion criteria
Exclusion criteria: • any physical condition potentially hampering compliance with the study protocol and follow-up schedule, this includes: severe visual impairment, total deafness or the inability to hold a pencil • personal time constraints unabling patients to comply to the study protocol • patients unable to comply with the outcome questionnaires (this includes insufficient knowledge of the Dutch language)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A change in cognitive functioning at two weeks, three months and one year postoperatively as measured by the Ruff Figural Fluency Test, Trailmaking Test and Rey's verbal learning test in comparison to the preoperative scores. | — |
Secondary
| Measure | Time frame |
|---|---|
| - postoperative delirium - postoperative complications - one year mortality - physical performance status - quality of life | — |
Contacts
Public ContactB.L. Leeuwen, van
University Medical Center Groningen (UMCG), Department of Surgery, P.O. Box 30.001
Outcome results
None listed