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A randomized, prospective, multicenter study of the effective treatments of panic disorder: cognitive behavioral versus antidepressants versus a combination therapy.

Short- and long-term effectiveness of three treatments for panic disorder: CBT, SSRI, or CBT+SSRI.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON26056
Enrollment
150
Registered
2006-06-09
Start date
2001-01-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Cognitive-Behavioral therapy (CBT)

Interventions

CBT: The CBT protocol is based on the work of Clark and Barlow. Patients in the CBT group received up to 21 CBT sessions each lasting approximately 50 minutes. From session 16 onwards, sessions were s

Sponsors

This study was initiated by the University Medical Center Groningen (UMCG).
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients suffering from a primary diagnosis of PD with or without AG (according to DSM-IV classification) recruited in 11 treatment facilities throug-out the Netherlands between 1 April 2001 and 1 October 2003.

Exclusion criteria

Exclusion criteria: 1. Comorbid Psychotic Disorder; 2. Drug dependence; 3. Major affective disorder; 4. Sifnificant risk of suicidality; 5. Pregnancy or lactation; 6. Contra-indications to either treatment modality.

Design outcomes

Primary

MeasureTime frame
Short-term: Hamilton Anxiety, Hamilton Depression, Frequency of Panic attacks, Responder status, SCL-90, Fear Questionnaire-subscale Agoraphobia. Long-term: remitter status, panic coping, quality of life, Hamilton Anxiety, Hamilton Depression.—

Secondary

MeasureTime frame
Treatment Satisfaction, Locus of Control. Fear of Bodily Sensations, Anticipation Anxiety, Negative and Positive Self statements.—

Contacts

Public ContactFranske J. Apeldoorn van

University Medical Center Groningen, P.O. Box 30.001

f.j.van.apeldoorn@psy.umcg.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)