Endocrine Disrupting Chemicals Prenatal exposure Prenatale blootstelling Childhood obesity Overgewicht op de kinderleeftijd
Conditions
Interventions
No intervention is planned as this is an observational study.
Sponsors
VU University Amsterdam
European Union: KBBE-2B-227391
Eligibility
Inclusion criteria
Inclusion criteria: Women eligible for participation should be living in the area of Zwolle and shoud be less than twelve weeks pregnant at their first visit to the midwifery clinic. They should be able to fill out Dutch questionnaires. Incapacitated subjects will not be asked to participate.
Exclusion criteria
Exclusion criteria: Women with pre-eclampsia or twin pregnancies are excluded from further participation. Preeclampsia is defined as pregnancy-induced hypertension (1x > diastolic pressure > 90 mmHg) in association with proteinuria (>0.3 g/day). Furthermore major congenital anomalies at birth will be reason for exclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is BMI at the age of twelve months in relation to levels of exposure markers of EDCs in cord blood. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Gestational age; 2. Birth weight; 3. Birth height; 4. Head circumference (at birth, 6 and 12 months); 5. Waist circumference (at birth, 6 and 12 months); 6. Asthma; 7. Allergies; 8. Neurodevelopment; 9. Behaviour, sleep, crying. | — |
Contacts
Public ContactMarijke Cock, de
VU University De Boelelaan 1085, room T-644
Outcome results
None listed