Coronary artery disease
Conditions
Interventions
After inclusion, patients will undergo coronary CT and OCT to determine if the residual stenosis is vulnerable. In case of vulnerable plaques at OCT, patients will be randomized to PCI with BVS placem
Sponsors
VU University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: · Informed consent must be obtained · Patients with STEMI or NSTEMI and residual, non-obstructive CAD, with the possibility of plaque vulnerability. · The coronary lesion must be suitable for PCI with a commercially available BVS.
Exclusion criteria
Exclusion criteria: · Refusal or inability to provide informed consent. · 4.0 mm · Anatomy or lesions unsuitable for OCT catheter crossing or imaging (aorta-ostial lesions, small diameter segment, severe calcifications) · Anatomy unsuitable for BVS placement (left main, bifurcation stenting, sidebranch (> 2 mm) involvement). · Target lesion is instent restenosis · Target lesion is chronic total occlusion · Severe kidney disease defined as an eGFR < 30 ml/min. · Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A composite of major adverse cardiovascular events (all cause mortality, non-fatal myocardial infarction (STEMI or NSTEMI), or unplanned revascularization) at one year follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| The same composite at 2 and 5 years | — |
Contacts
Public ContactNiels Royen, van
Department of Cardiology, VU University de Boelelaan 1117
Outcome results
None listed