Simple and safe exclusion of pulmonary embolism using quantitative D-dimer and Wells simplified decision rule.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON25993

Enrollment

879

Registered

2006-08-30

Start date

2002-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinically suspected pulmonary embolism.

Interventions

Upon clinical suspicion, Wells clinical decision rule was performed first and if patients had a score of 4.0 points, a D-dimer test followed. Patients with a normal D-dimer concentration had no furthe

Eligibility

Inclusion criteria

Inclusion criteria: Outpatients with clinically suspected PE.

Exclusion criteria

Exclusion criteria: 1. Anticoagulant therapy for more than 24 hours; 2. aged under 18 years; 3. pregnancy; 4. allergy to contrast media; 5. expected survival less than 3 months; 6. venous thromboembolism in the previous 6 months; 7. refusal or inability to consent.

Design outcomes

Primary

Measure	Time frame
Patients, in whom pulmonary embolism was excluded, were followed up for 3 months to document the occurrence of venous thromboembolic events or death.	—

Contacts

Public ContactR.J. Goekoop

Leiden University Medical Hospital C1-45 PO-box 9600

r.j.goekoop@lumc.nl+31 (0)71 5269111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)