None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-55 years; 2. Men and women; 3. Outpatient; 4. Meeting DSM-IV criteria for Intermittent Explosive Disorder; 5. Score on Overt Aggression Scale-Modified for Outpatient Use (MOAS) of ≥ 15 or score on Social Dysfucntion and Aggression Scale (SDAS) of ≥ 5.
Exclusion criteria
Exclusion criteria: 1. IQ < 84; 2. Lifetime history of (hypo)mania, schizophrenia, or delusional disorder; 3. Current major depression; 4. Current alcohol or substance dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main outcome of aggressive behavior will be the score on the Overt Aggression Scale-Modified for Outpatient Use (MOAS) and Social Dysfunction and Aggression Scale (SDAS). The MOAS and SDAS will be completed by different relevant informants. | — |
Secondary
| Measure | Time frame |
|---|---|
| During the pre-screening, the MOAS will be completed to examine if the participant meets the inclusion criteria. To examine if the participant does meet the inclusion and does not meet the exclusion criteria the M.I.N.I., SCID-II, CIDI, PPI, Mate-Crimi and NLV will be completed during the screening. For the baseline and follow-up measure of the interventions, the IOA will be conducted to measure social skills. The IPAS, RPQ, AQ, ZAV, HIT and PSAP will be used to measure the effect of the Anger Control Training. To assess psychomotor training, heart rate and skin conductance will be measured. In addition, neurocognitive tasks will be conducted to examine how responders and non-responders profiles relate to forms and correlates of aggressive behaviour. | — |
Contacts
Radboud University Nijmegen Medical Centre Department of Psychiatry, route 966 PO Box 9101