Esophageal cancer patients undergoing an esophagectomy
Conditions
Interventions
Strict nutrtional protocol consisting of:
• One dietitian: case manager during all stages of treatment
• Use PG-SGA-questionnaire before consult
• Weekly registration of nutritional intake
• Energ
Sponsors
University Medical Center Groningen
Secundary
Gelre Hospital Apeldoorn
Eligibility
Inclusion criteria
Inclusion criteria: • Patients that undergo a (minimally invasive or hybrid: laparoscopy and thoracotomy or conventional open surgery) esophagectomy for cancer with cervical or intrathoracic anastomosis • Written informed consent • Age > 18 years • Histologically confirmed, previously untreated esophageal cancer • Considered suitable for radical surgery with curative intent. • Squamous cell carcinoma, adenocarcinoma, and undifferentiated carcinoma are included. • Tumor location included the upper, middle, lower thirds of the esophagus and esophagogastric junction tumors, but excluded postcricoid cancers.
Exclusion criteria
Exclusion criteria: • Salvage esophagectomy; after previous histologically confirmed esophageal cancer treated by ‘definitive’ radio- or radiochemotherapy • Inability to provide written consent or inability to fill out questionnaires • Previous or concomitant malignant disease, apart from basal-cell carcinoma • Cervical lymph-node involvement or evidence of metastases. • Karnofsky Performance Status < 80
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sarcopenia (muscle loss) measured by psoas muscle index by a CT-scan | — |
Secondary
| Measure | Time frame |
|---|---|
| • Loss of muscle mass, measured by handgrip strength; arm circumference & triceps skinfold thickness; creatinin & urea in 24-hour urine. • Incidence of Clavien Dindo complications • Length of hospital stay and re-admittance rate • Survival • Quality of Life | — |
Contacts
Public ContactMarjo Campmans-Kuijpers
Afdeling Maag, darm- en leverziekten, BB041
Outcome results
None listed