Cervical dystonia, physical therapy,botulinum toxin, disability, functional status
Conditions
Interventions
Patients in the intervention group will receive Botuline Toxin (BTX) injection combined with a standardized PT program for 12 months consisting of muscle stretching, artherogenic mobilistions and exce
Sponsors
Academic Medical Center Amsterdam, University Medical Center Groningen, Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: 1. 100 patients with idiopathic CD; 2. 30 years or older; 3. Treated with botulinum toxin.
Exclusion criteria
Exclusion criteria: 1. Secondary (including psychogenic) dystonia; 2. Hereditary (dominant) forms of dystonia; 3. Segmental, hemi-, multifocal or generalized dystonia; 4. Patients who underwent neurosurgery; 5. Inability to understand written and spoken Dutch language; 6. Patients treated with the Bleton method by their physiotherapist at the moment of inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disability, measured with the Toronto Western Spasmodic Torticollis Rating Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Severity of dystonie, with the TSUI scale; 2. Pain, with a numeric rating scale; 3. Quality of life, with the Craniocervical dystonia Questionnaire 24; 4. Anxiety and depression with the Beck anxiety and depression inventory; 5. Healthcare costs and health utility with Quality Adjusted Life Years (QALY). | — |
Contacts
Public ContactJ. Dool, van den
AMC, Department of Neurology Meibergdreef 9 P.O box 22660
Outcome results
None listed