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Renal Transplant Patient Protein Oxidation Study

Protein oxidation in stable renal transplant patients measured with a breath test

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON25890
Enrollment
32
Registered
2017-12-06
Start date
2018-02-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

protein, metabolism, breath test, oxidation

Interventions

No intervention is given prior to the breath test

Sponsors

University Medical Center Groningen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18+ Male Be able to consume a 500 ml test drink within 5 minutes Be able to speak the Dutch language Give written informed consent Case: received renal transplant >6 months before the study Stable medication schedule for >2 weeks before the study (e.g. steroid use) Healthy control: donated kidney >6 months before the study

Exclusion criteria

Exclusion criteria: Milk (protein) allergy or intolerance Diabetes Cancer, except skin cancer Recreational drug use Active infection (CRP >10) Habitual average intake of more than 2 glasses of alcohol per day Not able to stop alcohol consumption 2 days before the breath test BMI 35

Design outcomes

Primary

MeasureTime frame
Percentage of given 30 g protein oxidized over 5,5 hours

Secondary

MeasureTime frame
Bloodsamples to measure: Glucose Insulin C-reactive protein Insulin-like growth factor 1

Contacts

Public ContactGerlof Reckman

Hanzeplein 1 UMCG

g.a.r.reckman@umcg.nl, g.a.r.reckman@pl.hanze.nl06 57 27 54 11

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)