Skip to content

Metacognitive training: A randomized controlled trial.

Metacognitive training: A randomized controlled trial to evaluate efficacy and cost-effectiveness of a training that aims to change cognitive biases that perpetuate psychosis in people with paranoid schizophrenia.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON25876
Enrollment
128
Registered
2010-04-28
Start date
2010-01-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosis paranoid schizophrenia

Interventions

Metacognitive Training (MCT): MCT is a group intervention intended for 3-10 patients. Sessions are typically conducted either by a clinical psychologist, psychiatrist, occupational therapist or psychi

Sponsors

Frans van Mierlo, MSc Division Manager Reinier van Arkelgroep Bethaniëstraat 2 5211 LJ 's Hertogenbosch The Netherlands +31-(0)73-6586111
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with schizophrenia and/or another psychotic disorder (established with SCAN); 2. With delusional symptoms (PANSS P1>3 & PSYRATS DRS 5>1 & PSYRATS DRS 6>1); 3. Aged between 18-65.

Exclusion criteria

Exclusion criteria: 1. Primary addiction; 2. Insufficient understanding of the Dutch language; 3. IQ<70.

Design outcomes

Primary

MeasureTime frame
Primary outcome: Paranoid ideas and ideas of social reference. The GPTS was chosen as primary outcome. The GPTS is a questionnaire that measures paranoid ideas and ideas of social reference with 32 items on a 5-point Likert-scale. The internal consistency is good, with a Crohnbach alpha > 0.70 and the test is consider valid.

Secondary

MeasureTime frame
Parameters: 1. Quality of life; 2. Subjective experience of cognitive biases; 3. Cognitive insight; 4. Delusional thinking; 5. Metacognitions; 6. Jumping-to-conclusionsbias; 7. Theory of mind; 8. Depression; 9. Memory bias. The EQ-5D is a standardized measure of health status developed by the EuroQoL Group in order to provide a simple, generic measure of health for clinical and economic appraisal. Applicable to a wide range of health conditions and treatments, it provides a simple descriptive profile and a single index value for health status that can be used in the clinical and economic evaluation of health care as well as in population health surveys. The Davos Assessment of Cognitive Bias Scale (DACOBS) is a questionnaire thath measures the subjective experience of cognitive bias using 42 items on a 7-point Likert-scale. The following cognitive biases are measured: the jumping-to-conclusions bias, dogmatism bias, selective attention bias and the self-as-target bias. In addition, there are questions regarding cognitive limitations and safety behaviors. The psychometric qualities of this questionnaire are currently being investigated. The Beck Cognitive Insight Scale (BCIS) is a 15-item self-report scale measuring 2 constructs: the ability to acknowledge fallibility, labeled self-reflectiveness and certainty about belief and judgments, labeled self-certainty. A composite score reflecting cognitive insight is calculated by subtracting the self-certainty scale from the self-reflectiveness scale. The BCIS has demonstrated good convergent, discriminant, and construct validity with inpatients. The PSYRATS DRS is a semi-structured interview whichs measures qualitative and quantitative aspects of delusions. The Metacognitions Questionnaire 30 (MCQ30) is a questionnaire that measures metacognitions via 30 items on a 4-point Likert-scale. The manual distinguishes between cognitive self-confidence, positive views, cognitive self-awareness, uncontrollability an

Contacts

Public ContactBas Oosterhout, van

Bethaniestraat 2

b.van.oosterhout@rvagroep.nl+31 (0)73 6586748

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)