preschool wheezing, asthma
Conditions
Interventions
questionnaires, lung function tests, throat swab
Sponsors
Amphia Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 6- to 9-year old children who were known for recurrent wheezing at the age of 1- to 4- years, treated by hospital-based pediatricians and included in our previous (WHEEP)study. Recurrent wheezing was defined as a minimum of 3 reported episodes in the year before inclusion, of which at least one must have been confirmed by a pediatrician.Children were then recruited from pediatric departments of ten general and academic hospitals in the Netherlands. During the 1-year (WHEEP)study period wheeze patterns were classified from patient diaries and compared to pediatrician assigned phenotypes
Exclusion criteria
Exclusion criteria: No new exclusion criteria. As in the former (WHEEP)study, children of whom their parents do not understand the Dutch language are not eligible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The predictive value of the phenotypes episodic viral wheeze and multiple trigger wheeze (clinical as well as diary-based) in the development of asthma | — |
Secondary
| Measure | Time frame |
|---|---|
| The occurrence of viral upper respiratory infections at preschool age and the risk of developing asthma, and differences in microbiome at preschool age between children who develop childhood asthma and children who do not. | — |
Contacts
Public ContactAnna Vaessen-Verberne
Amphia Hospital
Outcome results
None listed