X chromosome inactivation in human embryos obtained after either IVF or IVF/ICSI

X chromosome inactivation in human embryos obatined after either IVF or IVF/ICSI

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON25839

Enrollment

420

Registered

2008-04-25

Start date

2008-05-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IVF, ICSI, X chromosome inactivation, X chromosoom inactivatie

Interventions

The intervention on the embryos is intracytoplasmic sperm injection (ICSI), which is compared with conventional IVF. ICSI is a regular intervention used in case of male subfertility, where one spermat

Eligibility

Inclusion criteria

Inclusion criteria: 1. Human surplus embryos, not suitable for transfer or cryopreservation, originating from an IVF or ICSI treatment 2. Informed consent from patients

Exclusion criteria

Exclusion criteria: 1. Abnormal fertilized embryos 2. Presence of multinucleated blastomeres

Design outcomes

Primary

Measure	Time frame
X chromosome inactivation pattern in human surplus embryos	—

Secondary

Measure	Time frame
Comparison of time pattern of X chromosome inactivation between IVF and ICSI embryos	—

Contacts

Public ContactA. Montfoort, van

Maastricht University Medical Center Dept. of Obstetrics and Gynaecology Postbus 5800

aafke.van.montfoort@mumc.nl+ 31 43 3872012

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)