Effect of pre-operative pain treatment by means of duloxetine on postoperative outcome after total hip or knee arthroplasty- The DOA study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON25835

Enrollment

118

Registered

2014-08-15

Start date

2014-09-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

Preoperative treatment with Duloxetine for a period of 10 weeks

Eligibility

Inclusion criteria

Inclusion criteria: Primary hip or knee osteoarthitis, age above 18 years and a neuropathic pain profile

Exclusion criteria

Exclusion criteria: Surgical hip or knee procedure in previous year, hip or knee arthroscopy or injection past 3 months, unstable other medical condition, cognitive of neurological disorder or peripheral nerve injury, previous exposure to duloxetine

Design outcomes

Primary

Measure	Time frame
Degree of pain relief 6 months after total hip or knee arthroplasty	—

Secondary

Measure	Time frame
Degree of pain relief at other timepoints, specific neuropathic pain symptoms, functional improvement, physical activity, anxiety and depressive symptoms, quality of life and pain catastrophizing	—

Contacts

Public ContactM. Stevens

University Medical Center Groningen (UMCG) Department of Orthopaedic Surgery P.O. Box 30.001

m.stevens@umcg.nl+31 (0)50 3613271

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)