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The value of bronchodilators and anti-inflammatory medication in patients with posttraumatic rib fractures, a multicenter prospective cohort study (RIB-Inhalation)

The value of bronchodilators and anti-inflammatory medication in patients with posttraumatic rib fractures, a multicenter prospective cohort study (RIB-Inhalation)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON25831
Enrollment
100
Registered
2021-07-03
Start date
2021-09-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple rib fractures

Interventions

- Daily multiple times use of bronchodilators during primary hospital admission - No use of bronchodilators during primary hospital admission

Sponsors

Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age 16 years or older 2) Hospital admission with =3 rib fractures (CT-confirmed) after blunt chest trauma 3) Chest CT-scan within 24h after trauma 4) GCS score 15 5) Provision of informed consent by patient

Exclusion criteria

Exclusion criteria: 1) Use of bronchodilators in the last week before trauma 2) Known pregnancy 3) Previous thoracic surgery (e.g., lung resection) 4) Previous pulmonary problems, requiring continuous oxygen at home pre-trauma 5) Congenital thoracic deformity (e.g., pectus excavatum, pectus carinatum, severe scoliosis, or kyphosis) 6) Planned transfer to other hospital during primary admission 7) Insufficient comprehension of the Dutch language to understand the study documents in the judgement of the treating physician or research team

Design outcomes

Primary

MeasureTime frame
Pneumonia during primary hospital admission

Secondary

MeasureTime frame
- Pulmonary function (forced vital capacity and forced expiratory volume in 1 second), - Occurrence of thoracic complications - Occurrence of symptoms indicative of side effects of bronchodilators - Hospital length of stay

Contacts

Public ContactDr. Mathieu M.M. Wijffels

Erasmus MC, University Medical Center Rotterdam

m.wijffels@erasmusmc.nl+31107031050

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)