Exploration of the effects of HFS-induced secondary hyperalgesia on the NDT-EP method

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON25830

Enrollment

Registered

2021-09-14

Start date

2020-07-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

High Frequency Stimulation

Eligibility

Inclusion criteria

Inclusion criteria: (1) A signed, written informed consent; (2) Age between 16 and 40

Exclusion criteria

Exclusion criteria: (1) Participant refusal during the study; (2) Language problems; (3) Skin problems at site of stimulation or EEG recording; (4) Diabetes; (5) Implanted stimulation device; (6) Pregnancy; (7) Usage of analgesics within 24 hours before the experiment; (8) Excessive consumption of alcohol or drugs within 24 hours before the experiment; (9) Pain complaints at the time of the experiment; (10) (A medical history of) chronic pain

Design outcomes

Primary

Measure	Time frame
(1) Nociceptive Detection Thresholds (NDTs) (2) EEG signals (3) Numerical Rating Scale to mechanical punctate stimulation	—

Secondary

Measure	Time frame
(1) Participant characteristics (Age, sex, handedness) (2) Response time to stimuli (3) Electrode-skin impedance	—

Contacts

Public ContactNiels Jansen

University of Twente

n.jansen@utwente.nl+31 6 28 37 19 52

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)