Childhood cancer patients
Conditions
Interventions
None listed
Sponsors
Princess Máxima Center
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria patients: - Children, 6-17 years old - Currently undergoing chemotherapy Inclusion criteria controls (siblings): - Children, 6-17 years old
Exclusion criteria
Exclusion criteria: Exclusion criteria patients: - Children with isolated congenital anosmia (ICA; a complete loss of smell) - Children = 5 years - Children and parents that do not understand the Dutch language - Children with a self-reported allergy to quinine - Children with severe oral mucositis (treatment-induced ulceration of the mucosa, blis-tered tongue, and absence of saliva) Exclusion criteria controls: - Children with isolated congenital anosmia (ICA; a complete loss of smell) - Children = 5 years - Children and parents that do not understand the Dutch language - Children with a self-reported allergy to quinine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is feasibility of the study. Therefore we will test whether the lower age range is suitable to be tested. If not, for our next studies we will increase the lower age limit. The number of patients fully completing the study is the main endpoint. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Smell function - Taste function - Subjective smell and taste function (questionnaire) - Papillae density - Eating behaviour | — |
Contacts
Public ContactMirjam van den Brink
Prinses Maxima Center
Outcome results
None listed