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Developing methods for reconstructing electrical heart activity.

Developing mathematical methods for non-invasive reconstruction of electrical heart activity from body-surface electrocardiograms and a CT-based torso-heart geometry.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON25739
Enrollment
65
Registered
2011-08-08
Start date
2011-09-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac conduction disorder, heart rhythm disorders, hartritmestoornis, hartritmestoornissen, cardiac rhythm disorder

Interventions

The subjects will be asked to undergo a procedure in which 256 recordings of body-surface potentials (ECGs) are made. For this purpose, strips of electrodes will be attached to the subject's torso. Wh

Sponsors

Maastricht Universitair Medisch Centrum
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age ≥ 18 years and one or more of the following: 1. Conditions that might alter electrical conduction properties in the heart, including (but not limited to): Brugada syndrome (BS), Arrhythmogenic right ventricular cardiomyopathy (ARVC); 2. Implanted cardiac device, such as pacemaker or implantable cardioverter defibrillator; 3. The sole need for cardiac CT as technique to exclude cardiac disease (reference group).

Exclusion criteria

Exclusion criteria: Known strong reaction against electrode attachment.

Design outcomes

Primary

MeasureTime frame
The primary study endpoint is further development and validation of mathematical methods and recording techniques, to reconstruct epicardial potentials from body-surface potentials (BSPs) and a torso-heart geometry. This development and validation can only be performed when BSP and torso-heart geometrical data are available.

Secondary

MeasureTime frame
The secondary study endpoints include disease-specific abnormalities in epicardial reconstructions or in body-surface potential maps.

Contacts

Public ContactPaul Volders

Postbus 5800

p.volders@maastrichtuniversity.nl+31 (0)43 3875099

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)