Obesity, Diabetes Mellitus
Conditions
Interventions
None listed
Sponsors
Leiden University
Eligibility
Inclusion criteria
Inclusion criteria: • Healthy (self-reported) • Right-handed • Between 18 and 45 years old. • Having given their written informed consent • BMI between 18.5-30 kg/m2
Exclusion criteria
Exclusion criteria: • Having a history of or current alcohol consumption > 28 units per week • Daily smoking • Suffering from cold symptoms • Having a history of medical or surgical events that may significantly affect the study outcome, such as metabolic or endocrine disease, or any gastro-intestinal disorder • Mental or physical status that is incompatible with the proper conduct of the study • Not having a general practitioner • Participation in any other clinical trial during this study. • Common MRI exclusion criteria, including o Claustrophobia o Presence of metal in body incompatible with MRI scanning o Pacemaker o Being pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Neural activation in response to tasting sweet and sour solutions under high and low cognitive load measured with fMRI on time point 1 (study day) 2.Taste intensity and hedonic value ratings of the sweet and sour solutions under high and low cognitive load measured with 5-point Likert scale on time point 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Performance on the Stroop task (to measure attentional control) measured at time point 1 2. BMI measured at time point 1 3. Responses on the mobile Approach-Avoidance task (AAT) measured on the five days following the study day on time point 1 | — |
Contacts
Public ContactFloor van Meer
Leiden University
Outcome results
None listed