The validation of a clinical screening instrument for tumor predisposition syndromes in childhood cancer patients

The validation of a clinical screening instrument for tumor predisposition syndromes in childhood cancer patients: a prospective, observational, multi-center study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON25524

Enrollment

1000

Registered

2015-12-22

Start date

2016-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood Cancer Patients

Interventions

All the included patients will be invited for a consult with a genetic counselor. During this consult, the score form will be filled in and the medical photographer will make 2D and 3D pictures of the

Eligibility

Inclusion criteria

Inclusion criteria: - the age of 0 to 18 years - a newly diagnosed malignancy

Exclusion criteria

Exclusion criteria: - diagnosed with a syndrome, which is associated with the current malignancy

Design outcomes

Primary

Measure	Time frame
Sensitivity of the screening instrument	—

Secondary

Measure	Time frame
Specificity of the screening instrument, positive and negative predictive value, attribution of seperate parts of the screening instrument to the conclusion of the clinical geneticist.	—

Contacts

Public ContactF.A.M. (Floor) Postema

Secretariaat Kinderoncologie F8-178 - Tav. F. A. M. Postema

E-mail: f.a.m.postema@amc.nlTel: 020-5661689

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)