Acute myocardial infarction eligible for reperfusion therapy.
Conditions
Interventions
An infusion of 80 mmol potassium chloride in 500 ml 20 percent glucose with a rate of 2 ml/kilogram body weight/hour over an 12 hour period in a peripheral venous line (Appendix 1).
The infusion is s
Sponsors
Zwolle, Isala Klinieken, locatie Weezenlanden Dr J.H.E. Dambrink
Groningen, Academisch Ziekenhuis Dr S.A.J. van den Broek
AMC Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: Acute myocardial infarction diagnosed by: 1. Chest pain suggestive for acute myocardial infarction; 2. Symptom-onset 1 mV in 2 or more leads. Patients are eligible for either primary coronary angioplasty or thrombolysis. Patient who has given his or her informed consent to take part in the study.
Exclusion criteria
Exclusion criteria: 1. Unwillingness to participate; 2. Presence of heart failure (either one of these symptoms): a. Heart rate, > 90 beats/min; b. Systolic blood pressure < 100 mmHg with anterior myocardial infarction; c. Killip „d II (third heart sound, „d hand-wide rales).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30-day mortality (death from any cause and cardiovascular (death). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are one-year mortality, and analysis of pre-specified subgroups. | — |
Contacts
Public ContactJ. Klijn
Diagram B.V. Zwolle Dokter Stolteweg 96
Outcome results
None listed